Obstructive Uropathy and Hydronephrosis in Male KK-Ay Mice: A Report of Cases.
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چکیده
منابع مشابه
Obstructive uropathy and hydronephrosis in male KK-Ay mice: a report of cases.
Uropathy associated with hydronephrosis was observed frequently in our male KK-Ay mouse colony during a long-term study of diabetes. The lesion occurred in 24 of the 31 KK-Ay male mice and accounted for the greatest number of spontaneous deaths among them. It was observed after 4 months of age and involved about hard plugs of altered seminal material resembling the seminal vesicle secretion. Th...
متن کامل0 bstructive Vropathy and Hydronephrosis in Male KK - AY Mice : A Report ef Cases
ABs't'R,-cT, Uropathy asseciated with hydronephrosis was observed frequently in our male KK-AY mouse colony during long-term study of diabetes, The leslon occurred in 24 of the 3L KK-AY malc mice and accounted for the greatest number of spontaneeus deaths ameng them. It was observed aftcr 4 months of age and involved abeut hard plugs of altered seininal material resembLing the seminal vesicEe s...
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Primary causes of urinary tract obstruction that induces urine retention and results in hydronephrosis include uroliths, inflammation, and tumors. In this study, we analyzed the molecular pathology of ureteritis causing hydronephrosis in laboratory rodents.F2 progenies of C57BL/6 and DBA/2 mice were studied histopathologically and by comprehensive gene expression analysis of their ureters. Inci...
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متن کاملGenetic analysis of non-insulin-dependent diabetes mellitus in KK and KK-Ay mice.
The KK mouse is considered suitable as a polygenic model for human non-insulin-dependent diabetes mellitus. To identify the quantitative trait loci (QTLs) responsible for hyperglycemia and impaired glucose tolerance in KK mice, linkage analysis using 97 microsatellite markers was carried out in a 192 F2 progeny, comprising 93 mice with the a/a genotype at the agouti locus (chromosome 2) and 99 ...
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ژورنال
عنوان ژورنال: Journal of Veterinary Medical Science
سال: 1999
ISSN: 0916-7250,1347-7439
DOI: 10.1292/jvms.61.53